Most integrated circuits (ICs) of sufficient complexity use a clock signal in order to synchronize different parts of the circuit and to account for propagation delays. As ICs become more complex, the problem of supplying accurate and synchronized clocks to all the circuits becomes increasingly difficult. The preeminent example of such complex chips is the microprocessor, the central component of modern computers, which relies on a clock from a crystal oscillator. The only exceptions are asynchronous circuits such as asynchronous CPUs.
Didn't know about this before. Another one of those points of difference which raises interesting questions about the nature of neural versus digital computation.