Thursday, April 29, 2010

ATP Metabolism

And on the subject of overwhelming biological data, this is the IUBMB-Nicholson chart of all the metabolic pathways that go into ATP management in mitochondria and chloroplasts, ATP being the basic energy currency of biological systems. There's a browser-crashing full sized pdf at the link, or click the above thumbnail for a jpg.

Friday, April 23, 2010

The Long Tail of Life

Saved for future reference from

the Long Tail of Life: During an 11 month study in 2007, scientists sequenced the genes of more than 180,000 specimens from the Western English Channel. Although this level of sampling "far from exhausted the total diversity present," they wrote, one in every 25 readings yielded a new genus of bacteria (7,000 genera in all).

See also: Venter sequences the Sargasso Sea (and download the dataset here!); a review on the emerging field of metagenomics; genomic databases at NCBI (sequences of everything from the human genome to three strains of ebola); Helicos high-speed sequencing; a nice powerpoint on next-gen short-read sequencing and sequence assembly (including notes on Eulerian walks on De Bruijn graphs, the method used by sequence assembly algorithms like Velvet.) Man, guys, sequencing is the coolest.

Monday, April 12, 2010

Bicycle Built for Two Thousand

Bicycle Built For 2,000 is comprised of 2,088 voice recordings collected via Amazon's Mechanical Turk web service. Workers were prompted to listen to a short sound clip, then record themselves imitating what they heard. (more info)

(Daisy Bell was famously performed by an IBM 704 in 1962, in the world's first example of musical speech synthesis-- which is probably why Kubrick chose it for the end of 2001 as well.)